Mechanobiological simulations of prenatal joint morphogenesis

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Mechanobiological simulations of prenatal joint morphogenesis.

Joint morphogenesis is the process in which prenatal joints acquire their reciprocal and interlocking shapes. Despite the clinical importance of the process, it remains unclear how joints acquire their shapes. In this study, we simulate 3D mechanobiological joint morphogenesis for which the effects of a range of movements (or lack of movement) and different initial joint shapes are explored. We...

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ژورنال

عنوان ژورنال: Journal of Biomechanics

سال: 2014

ISSN: 0021-9290

DOI: 10.1016/j.jbiomech.2014.01.002